Influence of early posttraumatic hypothermia therapy on local cerebral blood flow and glucose metabolism after fluid-percussion brain injury
WEIZHAO ZHAO, OFELIA F. ALONSO., JUDITH Y. LOOR, RAUL BUSTO, AND MYRON D. GINSBERG
J Neurosurg, 1999
Rats were induced in either cranial hypothermia (30ºC) or normothermia (37ºC) for three hours after fluid-percussion head injury to assess local cerebral metabolic rate of glucose (LCMRglu) and local cerebral blood flow (LCBF). The LCMRglu/LCBF ratio was nearly doubled in the group that received cranial hypothermia relative to the rats that received normothermia.