LOCAL TRANSCUTANEOUS COOLING OF THE SPINAL CORD IN THE RAT: EFFECTS ON LONG-TERM OUTCOMES AFTER COMPRESSION SPINAL CORD INJURY

LOCAL TRANSCUTANEOUS COOLING OF THE SPINAL CORD IN THE RAT: EFFECTS ON LONG-TERM OUTCOMES AFTER COMPRESSION SPINAL CORD INJURY
RADOSLAV MOROCHOVI, MARIA CHUD A JANA TALANOV, PETER CIBUR MIROSLAV KITKA, IVO VANICKY
Intern. J. Neuroscience, 2008

Experimental animals were divided into hypothermic and normothermic groups. The assessment of neurologic recovery was performed once a week during a 4 weeks survival period. In consecutive cross-sectional areas, hypothermic animals had significantly more preserved white matter at the cranial periphery of the lesion. Mild posttraumatic hypothermia had some protective effect on tissue loss after spinal cord injury but this effect was not associated with functional improvement.