Maximizing neuroprotection: where do we stand?
Damien P Kuffler
Therapeutics and Clinical Risk Management, 2012
Many neurotoxicity triggers arise from common events, an approach for invoking more effective neuroprotection is to apply multiple neuroprotective methods simultaneously before the many neurotoxic triggers and cascades are initiated and become irreversible. Some neuroprotective mechanisms that block neurotoxicity, include hypothermia, alkalinization, and the administration of adenosine. Simultaneous application of these techniques provides significantly greater neuroprotection than is provided by any technique alone.