General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage
Heng Zhao, Gary K Steinberg and Robert M Sapolsky
Journal of Cerebral Blood Flow & Metabolism, 2007
Mild or moderate hypothermia is generally thought to block all changes in signaling events that are detrimental to the ischemic brain but the effects are variable. It has been confirmed that mild hypothermia is clinically feasible for acute focal stroke treatment but no definite benefits have been reported yet.