The effect of therapeutic hypothermia on the expression of inflammatory response genes following moderate traumatic brain injury in the rat
JS Truettner, T Suzuki, WD Dietrich
Molecular Brain research, 2005
Rats underwent moderate fluid-percussion brain injury with and without hypothermic treatment to detect genes that are differentially regulated after traumatic brain injury. Post-traumatic hypothermia had no significant effect on the acute expression of the majority of genes investigated but, the expression of TGF-beta2 at 24 h was significantly reduced by temperature manipulation.